Medical Science
Continuous Glucose Monitors Overestimate Blood Sugar Levels, Study Reveals
2025-03-04

A recent investigation into the accuracy of continuous glucose monitors (CGM) has uncovered significant discrepancies when compared to traditional capillary blood glucose measurements (CBGM). Conducted by a team of researchers and published in The American Journal of Clinical Nutrition, this study highlights how CGM devices tend to overestimate glycemic responses following meals. The research underscores the importance of understanding these differences for both diabetic individuals and health-conscious consumers.

Examining the Accuracy of Continuous Glucose Monitoring Devices

In a meticulously designed randomized crossover trial, 15 participants were monitored as they consumed various test foods and beverages. Researchers measured blood sugar levels using both CGM and CBGM methods at regular intervals over a two-hour period. Each participant underwent seven different carbohydrate tests, with a two-day gap between sessions to avoid overlapping effects. The results revealed that CGM consistently reported higher fasting and post-meal glucose levels compared to CBGM, with an average discrepancy of 0.9 mmol/L. Additionally, CGM indicated elevated blood sugar levels for four times longer than CBGM. The time to reach peak glucose concentration was also delayed by five to twelve minutes in CGM readings.

The type of food consumed significantly influenced the magnitude of these variations. For instance, the highest incremental area under the curve (iAUC) values were observed after consuming a 50-gram glucose solution, followed by a smoothie consumed over 30 minutes. Interestingly, CGM classified a commercial fruit smoothie as a high-GI product due to its higher iAUC value, whereas CBGM categorized it as moderate-GI. These findings suggest that the reliability of CGM for determining GI values is questionable, especially considering the variability introduced by different types of food and individual physiological differences.

Despite adjustments for baseline glucose levels, glucose tolerance, and body mass index, inter-individual variations still affected CGM measurements. This indicates that while CGM can provide valuable insights, it may not be entirely reliable for precise glycemic indexing without further refinement.

From a journalist's perspective, this study serves as a critical reminder of the need for caution when interpreting data from wearable health devices. While CGM offers convenience and real-time monitoring, its tendency to overestimate blood sugar levels could lead to unnecessary dietary restrictions or anxiety among users. Future research should focus on improving the accuracy of CGM devices and exploring whether certain models or brands perform better than others. Ultimately, this study emphasizes the importance of validating new technologies against established standards before widespread adoption.

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