In a significant development in pediatric healthcare, recent research highlights the critical need to reassess diagnostic practices for asthma in children. A groundbreaking study published in JAMA Network Open on February 28, 2025, reveals that traditional race-specific equations used in diagnosing lung function may inadvertently disadvantage Black children. These outdated methods can lead to under-diagnosis and delayed treatment, affecting long-term health outcomes.
The current diagnostic process for asthma involves multiple steps, starting with symptom reporting by caregivers or medical professionals. Children then undergo pulmonary function tests, which measure lung capacity using spirometers. These devices calculate expected lung function based on age, sex, body size, and race. However, this approach stems from flawed historical studies that inaccurately assumed racial differences in lung function. Consequently, these assumptions have led to adjustments in lung function calculations, potentially skewing results and perpetuating health disparities.
The introduction of new race-neutral equations by the Global Lung Initiative (GLI) Network in 2022 aims to rectify this issue. The updated equations eliminate race as a variable, providing a more equitable assessment of lung function. The study, led by Wan Chi Chang, MS, demonstrated that the race-neutral equation identified significantly more Black children with reduced lung function compared to the traditional race-specific method. This shift could ensure earlier and more accurate diagnoses, leading to timely interventions and better health outcomes for affected children.
Embracing the race-neutral equation is not just a step forward in medical practice; it is a commitment to justice and equality in healthcare. By adopting these updated guidelines universally, healthcare providers can address longstanding disparities and improve asthma diagnosis and treatment for all children. This change underscores the importance of continuous evaluation and adaptation in medical practices to ensure equitable care for every patient.